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ANA information: An ANA can be positive in people who have an autoimmune disease, but a negative ANA does not rule out an autoimmune disease, and there are MANY other reasons why an ANA can be positive. - 12.6–22.6% of healthy people have a positive ANA. - ANA often becomes positive as we age: up to 1/3 of adults over 65 have a positive ANA. - >90% of ANA-positive people never progress to a systemic autoimmune rheumatic disease. - Other things that can cause an ANA to be positive: medications, d
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