Acute myeloid leukemia (AML) is an aggressive blood cancer in which abnormal, immature cells build up in the bone marrow, ...

On the left are three forms of the same RNA molecule, which is stabilised into a single form (on the right) by mitoxantrone. Ribonucleic acids (RNAs) serve as messengers between DNA and protein ...

Ribonucleic acid, also called RNA, is a molecule present in all living cells. It plays a critical role in transmitting genetic instructions from DNA and creating proteins. With the power to execute a ...

Researchers engineered a programmable RNA base editor called ALTER from human Argonaute 2 fused to APOBEC3A, achieving stronger editing with fewer off-target effects than dCas13-based systems.

Contrary to historic understanding of RNA’s longevity in cells, some RNAs can persist in cells throughout the life of an organism. Lead authors, Martin Hetzer, PhD, president of the Institute of ...

Eight Myotis genomes connect unusual immune adaptations with DNA repair, cell death and dramatic differences in lifespan.

Immunologists from the Institute have been the first to uncover a role for a family of RNA binding proteins in the function of regulatory T cells in the immune system. As their name suggests, ...