Most microscopes can only illuminate objects down to a certain size before tiny features blur together. This blurring is known as the diffraction limit of light. Super-resolution imaging techniques, ...

Thymine suffers more UV damage than uracil in lab tests, but its damage pathways could help explain its place in DNA.

In recent years, technologies that allow scientists to study a person's DNA at single-molecule resolution have vastly expanded our knowledge of the human genome, the microbiome, and the genetic basis ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

Cryo-electron microscopy and single-molecule experiments show how phosphorylated M18BP1 relieves condensin II autoinhibition, enabling stable DNA binding and compaction in vitro.

A new review proposes that the DNA damage response drives PD-L1 upregulation in senescent cells, enabling immune evasion and ...

DNA Shield provides offline storage for critical digital assets, data that must remain unchanged and protected from emerging ...

Death does not make DNA disappear. Long after the heart has stopped and the brain has lost function, genetic material can remain inside cells and tissues. What changes is the environment around it: ...

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...

Gladstone Senior Investigator Vijay Ramani, PhD, (left) and collaborator Siva Kasinathan, MD, PhD, led a study that demonstrates how two new tools can perform single-cell genetic sequencing using less ...